Calcium hydrogen phosphate, particularly in the form of calcium hydrogen phosphate dihydrate (CaHPO4·2H2O) and anhydrous calcium hydrogen phosphate (CaHPO4), is used in the pharmaceutical industry for various purposes.
Calcium hydrogen phosphate is commonly used as a tablet excipient or filler in the pharmaceutical industry.It serves as a direct compression excipient, providing bulk and aiding in the compression of tablets.
Calcium hydrogen phosphate can act as a binder, helping to hold the ingredients of a tablet together, and as a disintegrant, promoting the breakup of the tablet into smaller particles upon ingestion.
Calcium hydrogen phosphate serves as a source of calcium in calcium supplements.Calcium is an essential mineral for bone health and overall well-being.
Calcium hydrogen phosphate can be used as a buffering agent in pharmaceutical formulations, helping to stabilize the pH of oral medications.
In addition to tablets, calcium hydrogen phosphate is used as a diluent in powder formulations, providing volume and aiding in the homogeneity of the powder.
Calcium hydrogen phosphate may be included in controlled release formulations to modulate the release of active pharmaceutical ingredients over time.
Due to its alkaline nature, calcium hydrogen phosphate can be included in antacid formulations to neutralize excess stomach acid.
In some cases, calcium hydrogen phosphate may be used in the preparation of intravenous medications.
Calcium hydrogen phosphate is sometimes incorporated into dental products, such as toothpaste, for its abrasive properties and potential benefits for oral health.
Calcium hydrogen phosphate can serve as a stabilizing agent for certain formulations, contributing to the physical and chemical stability of pharmaceutical products.
As a high-quality calcium compound, calcium hydrogen phosphate can be used as a pharmaceutical-grade calcium source in formulations where calcium supplementation is required.
The specific application of calcium hydrogen phosphate in pharmaceuticals can vary based on the formulation requirements, the type of medication, and the desired properties of the final product. The use of excipients like calcium hydrogen phosphate is carefully regulated to ensure the safety, efficacy, and quality of pharmaceutical products.